"Venopathy" at work: Recasting neointimal hyperplasia in a new light

Academic Article

Abstract

  • Hemodialysis vascular access is a unique form of vascular anastomosis. Although it is created in a unique disease state, it has much to offer in terms of insights into venous endothelial and anastomotic biology. The development of neointimal hyperplasia (NH) has been identified as a pathologic entity, decreasing the lifespan and effectiveness of hemodialysis vascular access. Subtle hints and new data suggest a contrary idea - that NH, to some extent an expected response, if controlled properly, may play a beneficial role in the promotion of maturation to a functional access. This review attempts to recast our understanding of NH and redefine research goals for an evolving discipline that focuses on a life-sustaining connection between an artery and vein. © 2010 Mosby, Inc. All rights reserved.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Yevzlin AS; Chan MR; Becker YT; Roy-Chaudhury P; Lee T; Becker BN
  • Start Page

  • 216
  • End Page

  • 225
  • Volume

  • 156
  • Issue

  • 4