Murine CD38: An immunoregulatory ectoenzyme

Academic Article

Abstract

  • CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.
  • Author List

  • Lund F; Solvason N; Grimaldi JC; Parkhouse RME; Howard M
  • Start Page

  • 469
  • End Page

  • 473
  • Volume

  • 16
  • Issue

  • 10