Risk factors for acquisition of endemic blastomycosis

Academic Article

Abstract

  • BACKGROUND: Blastomycosis is potentially fatal, but environmental risk factors for acquiring blastomycosis are not well established. METHOD: Matched cross-sectional questionnaire of 112 patients with history of blastomycosis and 118 control subjects in Manitoba and northwestern Ontario. RESULTS: The most common tissues involved with blastomycosis were pulmonary, skin and soft tissues, and bone. A significantly greater proportion of patients with blastomycosis than control subjects were involved in outdoor occupations. A significantly greater percentage of patients with blastomycosis were immunosuppressed either from collagen vascular disease or immunosuppressive therapy, or had hypothyroidism. A significant association between canine and human blastomycosis was not observed. CONCLUSIONS: Independent risk factors for development of blastomycosis included immunosuppression for any reason (including drugs or disease), collagen vascular disease, being an outdoor worker, and having a coworker with blastomycosis. Canine blastomycosis was not a risk factor for human disease in dog owners. ©2009 Pulsus Group Inc. All rights reserved.
  • Digital Object Identifier (doi)

    Author List

  • Choptiany M; Wiebe L; Limerick B; Sarsfield P; Cheang M; Light B; Hammond G; MacDonald K; Trepman E; Pappas P
  • Start Page

  • 117
  • End Page

  • 121
  • Volume

  • 20
  • Issue

  • 4