Serum antibodies to pneumococcal neuraminidase NanA in relation to pneumococcal carriage and acute otitis media

Academic Article


  • Pneumococcal neuraminidase, NanA, is a pneumococcal vaccine candidate. Prior culture-confirmed pneumococcal contacts were shown to induce serum anti-NanA antibodies during the first 2 years of life. The antibody concentrations at neither 12 nor 18 months were significantly associated with the risk of subsequent pneumococcal carriage or acute otitis media. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Simell B; Jaakkola T; Lahdenkari M; Briles D; Hollingshead S; Kilpi TM; Käyhty H
  • Start Page

  • 1177
  • End Page

  • 1179
  • Volume

  • 13
  • Issue

  • 10