Does central nervous system toxicity occur in transplant patients with hypocholesterolemia receiving cyclosporine

Academic Article


  • A syndrome of severe central nervous system toxicity (confusion, cortical blindness, quadriplegia, seizures, and coma) associated with cyclosporine therapy and a low serum cholesterol level in patients with liver transplants has been described. We present a case history of a patient who demonstrated several similar features after heart-lung transplantation. Possible cyclosporine neurotoxicity should be considered in any patients with hypocholesterolemia receiving this drug.
  • Authors

    Pubmed Id

  • 21451166
  • Author List

  • Cooper DKC; Novitzky D; Davis L; Huff JE; Parker D; Schlesinger R; Sholer C; Zuhdi N
  • Start Page

  • 221
  • End Page

  • 224
  • Volume

  • 8
  • Issue

  • 3