Prolonged Hypotension After Initial Minoxidil Dose

Academic Article


  • • Severe prolonged hypotension developed in a hypertensive patient several hours after the initial doses of minoxidil therapy. Hemodynamic measurements revealed a markedly low systemic vascular resistance and a markedly high cardiac output. Other causes of hypotension were ruled out. The patient’s hemodynamic abnormalities lasted three days after minoxidil therapy was discontinued, and she then reverted to hypertension. Thus, a 10-mg starting dose of minoxidil may produce profound life-threatening hypotension, which can last up to 72 hours. © 1986, American Medical Association. All rights reserved.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 14280270
  • Author List

  • Allon M; Hall WD; Macon EJ
  • Start Page

  • 2075
  • End Page

  • 2076
  • Volume

  • 146
  • Issue

  • 10