Neonatal Intensive Care Unit Length of Stay Reduction by Heart Rate Characteristics Monitoring

Academic Article


  • Objective: To examine the effect of heart rate characteristics (HRC) monitoring on length of stay among very low birth weight (VLBW; <1500 g birth weight) neonates in the HeRO randomized controlled trial (RCT). Study design: We performed a retrospective analysis of length of stay metrics among 3 subpopulations (all patients, all survivors, and survivors with positive blood or urine cultures) enrolled in a multicenter, RCT of HRC monitoring. Results: Among all patients in the RCT, infants randomized to receive HRC monitoring were more likely than controls to be discharged alive and prior to day 120 (83.6% vs 80.1%, P =.014). The postmenstrual age at discharge for survivors with positive blood or urine cultures was 3.2 days lower among infants randomized to receive HRC monitoring when compared with controls (P =.026). Although there were trends in other metrics toward reduced length of stay in HRC-monitored patients, none reached statistical significance. Conclusions: HRC monitoring is associated with reduced mortality in VLBW patients and a reduction in length of stay among infected surviving VLBW infants. Trial registration: NCT00307333.
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    Author List

  • Swanson JR; King WE; Sinkin RA; Lake DE; Carlo WA; Schelonka RL; Porcelli PJ; Navarrete CT; Bancalari E; Aschner JL
  • Start Page

  • 162
  • End Page

  • 167
  • Volume

  • 198