COMPUTERIZED HEMODYNAMIC AND ELECTROPHYSIOLOGIC CLINICAL STUDIES IN A MYOCARDIAL INFARCTION RESEARCH UNIT - FIVE YEARS EXPERIENCE.

Academic Article

Abstract

  • A computerized physiologic data collection, analysis and display system has been used to support both clinical studies and routine patient care in the setting of an acute medical cardiovascular care unit for over 5 years. Measurements of pulmonary arterial, pulmonary wedge, right atrial and systemic arterial pressures; thermal dilution cardiac outputs; and R-R intervals, A-A intervals and QRS durations are available at the bedside. Clinical studies supported by this system have included: 1) identification of hemodynamic disturbances in acute myocardial infarction; 2) assessment of left ventricular function in unstable ischemic heart disease; 3) demonstration of the hemodynamic effects of pharmacologic and metabolic interventions; 4) investigation of cyclic electrophysiologic phenomenon and 5) evaluation of antiarrhythmic interventions. Newer applications are: 1) addition of a bipolar atrial electrogram channel for continuous atrial monitoring; 2) calculation of the acute myocardial infarction size by the creatine phosphokinase technique; and 3) radioisotope image processing and enhancement for quantitative measurements of infarction size and ventricular function.
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    Author List

  • Mantle JA; Strand EM; Wixson SE; Smith LR; Rogers WJ; Russell RO; Rackley CE
  • Start Page

  • 95
  • End Page

  • 99