Introduction: This literature review summarizes the current evidence on educational interventions to develop healthcare worker resilience. Methods: Electronic databases were systematically searched using the search terms: education OR training OR medical students AND resilience. The initial search was refined using criteria including population (healthcare students and professionals), interventions (educational), and outcome (resilience changes). Results: Resilience has been defined and measured in various ways. The following educational interventions to develop resilience were identified: resilience workshops, small group problem solving, reflection, cognitive behavioral training, mindfulness and relaxation training, and mentoring. Conclusions: The strongest evidence was for using resilience workshops, cognitive behavioral training, or a combination of interventions. The literature is sometimes conflicting suggesting that developing resilience is a complex process, and our understanding is not fully developed.