Objective: To examine relationships between spiritual health locus of control beliefs and various health behaviors. Methods: A cross-sectional survey of a national sample of African Americans assessed spiritual beliefs, fruit and vegetable consumption, physical activity, and alcohol consumption. Results: Active spiritual beliefs were positively associated with fruit consumption and negatively associated with alcohol consumption. Passive spiritual beliefs were associated with lower vegetable and increased alcohol consumption. Among male participants, passive spiritual beliefs were associated with higher alcohol consumption. Conclusions: Findings suggest that dimensions of spiritual health locus of control beliefs have complex and varying relationships with health behaviors.