Pulmonary 'cyclosporinoma' mimicking infection after heart transplantation

Academic Article


  • Tissue from a transthoracic needle biopsy, which was performed as part of the investigation of an undiagnosed left upper lobe opacity in a patient after orthotopic heart transplantation, revealed numerous macrophages loaded with oil globules. No causative organisms were present. High-pressure liquid chromatography showed a similar profile to the oil in which cyclosporine is suspended. The lesion appears to have been caused by aspiration of cyclosporine.
  • Pubmed Id

  • 15203614
  • Author List

  • Gould K; Freeman R; Odom NJ; Locke TJ; McGregor CGA
  • Start Page

  • 375
  • End Page

  • 377
  • Volume

  • 6
  • Issue

  • 6