Purpose. In ophthalmology, there is no system to objectively evaluate injury severity. The goal of this project is to design, test, and validate an Ocular Trauma Score (OTS) for rapid clinical assessment of eye injuries to guide triage, predict functional outcome, facilitate rehabilitation and standardize research. Methods. This 3-year study will analyze more than 3,000 injuries from the United States Eye Injury Registry (USEIR); the system will be developed based on existing cases and tested on prospectively collected injuries, incorporating initial information such as specific tissue injuries and different functional variables (e.g., visual acuity, intraocular pressure). Categories of the final vision will be used as the endpoint, Clinical experience of multiple ocular trauma experts as well as results of various statistical analyses will help develop specific weights on a scale; these will then be combined into a single overall score to characterize the injury's severity. Results. A pilot study on 157 injuries using classification and regression tree analysis and logistic regression analysis identified poor initial vision, corneoscleral rupture, globe perforation, presence of an afferent pupillary defect, hemorrhagic retinal detachment, and optic nerve injury as predictors of poor visual outcome. Conclusions. The OTS is expected to help standardize eye injury severity assessment, similar to the Glasgow Coma Score in head trauma. This scoring system can then be used to predict outcomes and evaluate the effects of preventive, acute care, and rehabilitative interventions.