Objectives: This article describes successful institutionally based programs for providing high-quality palliative care to persons with cancer and their family members. Challenges and opportunities for program development are also described. Data Sources: Published literature from 2000 to present describing concurrent oncology palliative care clinical trials, standards, and guidelines were reviewed. Conclusion: Clinical trials have shown feasibility and positive outcomes and formed the basis for consensus guidelines that support concurrent oncology palliative care models. Implications for Nursing Practice: Oncology nurses should advocate for all patients with advanced cancer and their families to have access to concurrent oncology palliative care from the time of diagnosis with a life-limiting cancer. © 2010 Elsevier Inc.