Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise

Academic Article


  • We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was significantly higher following CNTRL.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 9869957
  • Author List

  • Layne AS; Larkin-Kaiser K; MacNeil GG; Dirain M; Sandesara B; Manini TM; Buford TW
  • Start Page

  • 68
  • End Page

  • 76
  • Volume

  • 42
  • Issue

  • 1