Cloning of rat calcium-modulating cyclophilin ligand

Academic Article

Abstract

  • Rat calcium-modulating cyclophilin ligand (CAML) cDNA was cloned and sequenced. It has a predicted open reading frame of 294 amino acids. The CAML gene is highly conserved throughout species, showing 85, 89 and 69% amino acid sequence identity to the human, mouse, and chicken genes, respectively. Gene expression data using astrocytes, microglia and neurons show that CAML mRNA and protein is constitu-tively expressed in these cell types of the central nervous system. The cloning of rat CAML will facilitate further investigations on the function of this molecule. © 2001 OPA (Overseas Publishen Aswciatinn) N V.
  • Digital Object Identifier (doi)

    Author List

  • Lee SJ; Drabik K; Benveniste EN
  • Start Page

  • 209
  • End Page

  • 213
  • Volume

  • 12
  • Issue

  • 3