Nitric oxide in paraventricular nuclei of rat hypothalamus under extreme conditions

Academic Article


  • The activity of nitroxide synthetase (NOS) was studied histochemically and levels of oxytocin and vasopressin immunocytochemically in rat hypothalamus paraventricular nuclei in on-earth experiments simulating space flight conditions with landing. Colonization of oxytocin and NOS was found in large-cell neurons of paraventricular nuclei. After 15 days under conditions of simulated microgravitation followed by 1-day double gravitation and a short-term (1 day) macrogravitation, activities of NOS and content of neuropeptides increased in large-cell neurons of paraventricular nuclei of experimental animals. ©1998 Plenum Publishing Corporation.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Fidelina OV; Gorbatyuk OS; Akmaev IG
  • Start Page

  • 248
  • End Page

  • 250
  • Volume

  • 125
  • Issue

  • 3