Honoring 50 years of clinical heart transplantation in Circulation: In-depth state-of-the-art review

Academic Article


  • Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.
  • Authors

    Published In

  • Circulation  Journal
  • Digital Object Identifier (doi)

    Author List

  • Stehlik J; Kobashigawa J; Hunt SA; Reichenspurner H; Kirklin JK
  • Start Page

  • 71
  • End Page

  • 87
  • Volume

  • 137
  • Issue

  • 1