Added effects of organ (heart) storage after brain death in the experimental animal

Academic Article


  • Studies of myocardial ischemia after experimental brain death are reported below. The induction of brain death resulted in deterioration of myocardial function and depletion of energy reserves. Twenty-four-hour hypothermic perfusion storage of freshly excised hearts did not result in significant changes in myocardial function, but hearts excised from brain-dead animals and subsequently stored showed significant functional changes. The reduction in function was more severe when intravenous (IV) fluids and dobutamine or vasopressin were administered to maintain the blood pressure in the brain-dead animal.
  • Authors

    Published In

    Author List

  • Wicomb WN; Cooper DKC; Novitzky D
  • Start Page

  • 39
  • End Page

  • 43
  • Volume

  • 20
  • Issue

  • 5 SUPPL. 7