Thyroid hormone therapy and procurement of livers from brain-dead donors

Academic Article


  • © 2016 Taylor & Francis. ABSTRACT: Hormonal therapy to brain-dead potential organ donors remains controversial. A retrospective study was carried out of hormonal therapy on procurement of organs in 63,593 donors in whom information on T3/T4 therapy was available. In 40,124 donors, T3/T4 and all other hormonal therapy was recorded. The percentages of all organs procured, except livers, were greater in T3/T4-treated donors. Nevertheless, if T3/T4 therapy had been administered to the donor, liver transplantation was associated with significantly increased graft and recipient survival at 1 month and 12 months. The potential reasons for the lack of effect of T3/T4 therapy on the number of livers procured are discussed.
  • Authors

    Published In

  • Endocrine Research  Journal
  • Digital Object Identifier (doi)

    Author List

  • Novitzky D; Mi Z; Videla LA; Collins JF; Cooper DKC
  • Start Page

  • 270
  • End Page

  • 273
  • Volume

  • 41
  • Issue

  • 3