Intra-operative correction of acidosis, coagulopathy and hypothermia in combat casualties with severe haemorrhagic shock

Academic Article

Abstract

  • We assessed acidosis, coagulopathy and hypothermia, before and after surgery in 51 combat troops operated on for severe blast injury. Patients were transfused a median (IQR [range]) of 27 (17-38 [5-84]) units of red cell concentrate, 27 (16-38 [4-83]) units of plasma, 2.0 (0.5-3.5 [0-13.0]) units of cryoprecipitate and 4 (2-6 [0-17]) pools of platelets. The pH, base excess, prothrombin time and temperature increased: from 7.19 (7.10-7.29 [6.50-7.49]) to 7.45 (7.40-7.51 [7.15-7.62]); from -9.0 (-13.5 to -4.5 [-28 to -2]) mmol.l to 4.5 (1.0-8.0 [-7 to +11]) mmol.l ; from 18 (15-21 [9-24]) s to 14 (11-18 [9-21]) s; and from 36.1 (35.1-37.1 [33.0-38.1]) °C to 37.4 (37.0-37.9 [36.0-38.0]) °C, respectively. Contemporary intra-operative resuscitation strategies can normalise the physiological derangements caused by haemorrhagic shock. © 2013 Crown copyright. This article is published with the permission of the Controller of HMSO and the Queens Printer for Scotland. -1 -1
  • Authors

    Published In

  • Anaesthesia  Journal
  • Digital Object Identifier (doi)

    Author List

  • Morrison JJ; Ross JD; Poon H; Midwinter MJ; Jansen JO
  • Start Page

  • 846
  • End Page

  • 850
  • Volume

  • 68
  • Issue

  • 8