Results of a pilot multicenter genotype-based randomized placebo-controlled trial of propranolol to reduce pain after major thermal burn injury.

Academic Article


  • Background: Results of previous studies suggest that β-adrenoreceptor activation may augment pain, and that β-adrenoreceptor antagonists may be effective in reducing pain, particularly in individuals not homozygous for the catechol-O-methyltransferase (COMT) high-activity haplotype.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Orrey DC; Halawa OI; Bortsov AV; Shupp JW; Jones SW; Haith LR; Hoskins JM; Jordan MH; Bangdiwala SI; Roane BR
  • Start Page

  • 21
  • End Page

  • 29
  • Volume

  • 31
  • Issue

  • 1