This article presents findings from a study of the reliability and validity of the Student Risk Screening Scale for use with high school students (N = 674). Results revealed high internal consistency, test-retest stability, interrater reliability, and convergent validity with the Strengths and Difficulties Questionnaire. Predictive validity was established across two academic years, with students at low risk for antisocial behavior differentiated on behavioral (office discipline referrals [ODR]) and academic variables (grade point average [GPA]) from students with moderate and high levels of risk. However, neither ODR nor GPA variables could differentiate between students with moderate-risk or high-risk status. Limitations and future research directions are discussed. © 2008 Hammill Institute on Disabilities.