Resting thallium-201 myocardial perfusion patterns in patients with severe left ventricular dysfunction: Differences between patients with primary cardiomyopathy, chronic coronary artery disease, or acute myocardial infarction

Academic Article

Abstract

  • This study examined the value of resting thallium-201 imaging in differentiating patients with primary cardiomyopathy from those with ischemic cardiomyopathy. There were 15 patients with primary cardiomyopathy (group I); 20 with chronic CAD (group II); and 25 with acute Q wave myocardial infarction (group III). All patients had LVEF ≤ 35%. The thallium score was <50 (maximum 60) in one patient (7%) in group I, in 17 patients (85%) in group II, and in 25 patients (100%) in group III (p < 0.0001, I vs II and III). The number of normal segments was 11.4 ± 4.9 in group I, 6.9 ± 2.9 in group II, and 7.0 ± 2.2 in group III (p < 0.0001, I vs II, III). Reversible defects were present in three patients in group II, three in group III, and none in group I. Abnormal right ventricular thallium uptake was observed in 27% of patients in group I, 25% in group II, and 40% in group III (p = NS). Abnormal lung thallium uptake was observed in 33% in group I, 20% in group II, and 20% in group III (p = NS). Thus, rest thallium imaging is useful in separating patients with primary cardiomyopathy from those with ischemic cardiomyopathy. © 1986.
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    Digital Object Identifier (doi)

    Author List

  • Iskandrian AS; Hakki AH; Kane S
  • Start Page

  • 760
  • End Page

  • 767
  • Volume

  • 111
  • Issue

  • 4