Speed of processing training in middle-aged and older breast cancer survivors (SOAR): results of a randomized controlled pilot

Academic Article


  • Purpose: Cognitive changes are common among breast cancer survivors. There is limited evidence to guide management of cognitive changes. This randomized controlled pilot evaluated the preliminary efficacy of a speed of processing (SOP) training among middle-aged and older breast cancer survivors. Methods: Sixty breast cancer survivors with self-reported cognitive changes were recruited to the SOAR study. Participants were randomized to either a home-based SOP training (n = 30) or no-contact control group (n = 30). Primary outcomes were SOP (Useful Field of View Test ® ), and executive function (NIH Toolbox Cognition Battery). Neuropsychological assessments were completed at baseline, 6 weeks, and 6 months post study entry. Data were analyzed using repeated measures t tests, analysis of covariance, and sensitivity analyses. Results: SOP training resulted in improvement in objective measures of SOP and executive function. Immediate (6 week) posttest and 6-month follow-up demonstrated large SOP training effects over time. Large representation of African American women (51.2%) and 96% retention in the SOAR study add to study strengths. Conclusion: Home-based SOP training shows promise for remediating cognitive changes following breast cancer treatment, particularly improved SOP, and executive function.
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    Digital Object Identifier (doi)

    Author List

  • Meneses K; Benz R; Bail JR; Vo JB; Triebel K; Fazeli P; Frank J; Vance DE
  • Start Page

  • 259
  • End Page

  • 267
  • Volume

  • 168
  • Issue

  • 1