Prevalence of measles antibodies in asymptomatic human immunodeficiency virus-infected adults

Academic Article

Abstract

  • One hundred five asymptomatic human immunodeficiency virus-seropositive adults were screened for measles antibody. Ages ranged from 21 to 59 years (mean, 35.7). CD4+ lymphocyte counts (range, 76-1137/mm3), percentage of CD4+ cells (6-42), CD4:CD8 ratio (0.08-1.3), measles antibody titers by EIA, and undocumented history of prior measles or immunization were obtained. Forty-six patients gave a history of measles but no immunization, 18 of immunization but no measles, 26 of immunization and measles, and 15 of neither measles nor vaccination. Only one patient (<1%) lacked levels of antibody considered protective. Neither the presence nor the level of antibody were predictable from patient age, history of measles or immunization, CD4+ lymphocyte count, percentage of CD4+ cells, or CD4:CD8 ratio. Nearly all subjects had antibody to measles, regardless of immunization or measles history. Whether these antibodies are truly protective is unknown.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 27586181
  • Author List

  • Sha BE; Harris AA; Benson CA; Atkinson WL; Urbanski PA; Stewart JA; Williams WW; Murphy RL; Phair JP; Levin SA
  • Start Page

  • 973
  • End Page

  • 975
  • Volume

  • 164
  • Issue

  • 5