Attitudes and practices regarding marijuana use are examined in a sample of Mexican-American and Anglo adolescents living in Wyoming. The Mexican-American respondents were matched with Anglos who shared similar social and demographc characteristics, and matched-set analysis was used to determine significant differences on the basis of racial/ethnic identity. On all measures, Mexican-American youth were found to have significantly more positive attitudes toward marijuana and more extensive marijuana use. The implications of these findings are discussed. © 1983 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.