Microbially-produced peptides having potential application to the prevention of dental caries

Academic Article


  • Strategies advanced to decrease the occurrence of dental caries have in the past typically focussed upon attempting to reduce plaque accumulation by application of bread-spectrum antibacterial agents. In recent years however there has been growing interest in the application of a more targeted approach to the selective elimination from plaque of those bacterial species that are specifically implicated as the aetiological agents of this disease. This review focuses upon a number of the small bacterially-produced peptide antibiotics known as bacteriocins that are currently being explored for their potential role in the treatment and prevention of dental caries.
  • Digital Object Identifier (doi)

    Author List

  • Chikindas ML; Nov├ík J; Caufield PW; Schilling K; Tagg JR
  • Start Page

  • 95
  • End Page

  • 105
  • Volume

  • 9
  • Issue

  • 2