NemR is a bleach-sensing transcription factor

Academic Article

Abstract

  • Background: Little is known about how bacteria sense or respond to reactive chlorine species, such as bleach. Results: NemR is a redox-regulated transcription factor which senses bleach. Conclusion: NemR controls expression of genes encoding electrophile detoxification enzymes, which increase bleach resistance. Significance: We demonstrate a bleach-sensing bacterial response system and a new mechanism contributing to bacterial bleach survival. Copyright © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Gray MJ; Wholey WY; Parker BW; Kim M; Jakob U
  • Start Page

  • 13789
  • End Page

  • 13798
  • Volume

  • 288
  • Issue

  • 19