Cost-effective airway cultures in the cystic fibrosis patient

Academic Article


  • Background: Cystic fibrosis (CF) patients have a high incidence of multidrug-resistant infections, rendering CF patients a treatment challenge. Objective: To evaluate culture protocols for CF patients and develop a cost-effective culture regimen that identifies clinically relevant pathogens. Study design: Retrospective review. Methods: At the time of endoscopic sinus surgery, CF patients underwent both sinus and bronchial lavage cultures. Medical records from 2002 to 2006 were reviewed. Results: Twenty-four cases were identified; 12 had complete sets of cultures. Seven of 12 had sinus aerobic bacteria that were also present in bronchial culture. Anaerobic cultures from both sites were all negative (42%) or nondiagnostic (58%). Thirty-three percent of sinus fungal cultures and 91.6% of bronchial fungal cultures were positive. Sinus acid fast bacillus cultures were all negative. Conclusion: CF culture protocols may be streamlined by eliminating all anaerobic cultures, as well as sinus acid fast bacillus and fungal cultures for a 52% reduction in cost. © 2009 Elsevier Inc. All rights reserved.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 25809376
  • Author List

  • Ghegan MD; Wise SK; White DR; Flume PA; Bowman CM; Virella-Lowell I; Schlosser RJ
  • Start Page

  • 150
  • End Page

  • 152
  • Volume

  • 30
  • Issue

  • 3