X-ray diffraction studies on tungsten and molybdenum were performed, using a 4-μm-diam x-ray beam, to very high pressures, with the pressures being obtained from the measured lattice parameters and isothermal equations of state of tungsten and molybdenum deduced from shock data. The bcc structure persists to the highest pressure, 378 GPa in tungsten, and 416 GPa in molybdenum. The static pressures generated and measured here exceed the pressure of 361 GPa at the center of the earth, the first time that this has been achieved and measured with a calibrated pressure scale. The details of the pressure profile at 335 GPa are shown and are of great use in designing anvils for future research. It is noted that the maximum pressures attained by x-ray diffraction with beveled anvils varies linearly with D-1/2 where D is the diameter of the flat suggesting that, perhaps, even higher pressures are possible with further miniaturization. A scaling law is used to calculate the minimum correction due to the presence of nonhydrostatic stress.