Four trends in tunable lasers based on color center and radiationally pertubed doped crystals are reported. The first trend takes advantage of optimizing the processes of radiational coloration of the crystals and color center stabilization. The second new trend is connected with the development of highly concentrated LiF color center crystals with a wave guide thin film geometry. The third new trend is composed of a novel color center laser optical cavity, providing superbroadband generation across the whole emission region of the LiF:F-2 active medium. The fourth trend relates to new promising laser media based on radiationally pertubed Sc-doped crystals.