Elucidation of the antigenic determinant in lipotropin for two monoclonal antibodies

Academic Article

Abstract

  • Two monoclonal antibodies were found to give enhanced affinity for β-lipotropin when mixed, as evidenced by competitive radioimmunoassay. Both monoclonals were found to react with a pentapeptide Ala-Glu-Leu-Glu-Tyr, which is a sequence of high local hydrophilicity within the N-terminal section of β-lipotropin. © 1983.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 9917460
  • Author List

  • Austen BM; Lorenz R; Spitz M; Thorpe R
  • Start Page

  • 527
  • End Page

  • 533
  • Volume

  • 116
  • Issue

  • 2