Hippocampal dentation: Structural variation and its association with episodic memory in healthy adults

Academic Article

Abstract

  • © 2017 Elsevier Ltd While the hippocampus has long been identified as a structure integral to memory, the relationship between morphology and function has yet to be fully explained. We present an analysis of hippocampal dentation, a morphological feature previously unexplored in regard to its relationship with episodic memory. “Hippocampal dentation” in this case refers to surface convolutions, primarily present in the CA1/subiculum on the inferior aspect of the hippocampus. Hippocampal dentation was visualized using ultra-high resolution structural MRI and evaluated using a novel visual rating scale. The degree of hippocampal dentation was found to vary considerably across individuals, and was positively associated with verbal memory recall and visual memory recognition in a sample of 22 healthy adults. This study is the first to characterize the variation in hippocampal dentation in a healthy cohort and to demonstrate its association with aspects of episodic memory.
  • Published In

  • Neuropsychologia  Journal
  • Digital Object Identifier (doi)

    Author List

  • Fleming Beattie J; Martin RC; Kana RK; Deshpande H; Lee S; Curé J; Ver Hoef L
  • Start Page

  • 65
  • End Page

  • 75
  • Volume

  • 101