Objective: A substantial increase in the number of nonpowered and powered scooter injuries since 2000 has occurred in the United States. Because of differences in weight and operational speed between scooter types, it is possible that the type and severity of injuries may differ. The purpose of the current study is to compare demographics and injury characteristics between scooter types, focusing on differences in injury severity. Methods: The 2002-2006 National Electronic Injury Surveillance System provided information about individuals aged 2 to 12 years who sought treatment at an emergency department due to powered or nonpowered scooter-related injury in the United States. We defined severe injury as an injury resulting in the hospitalization, staying in the hospital for observation, or transfer of the injured patient. Logistic regression analysis, adjusted for sex, age, and geographic location in which the injury occurred, estimated odds ratios (ORs) and 95% confidence intervals (CI) for the association between scooter type and severe injury. Results: There were an estimated 15 752 and 185 007 injuries related to powered and nonpowered scooters, respectively. Powered scooter-related injuries were over 3 times as likely to be severe (OR 3.57, 95% CI, 1.91-6.65). This association was more prominent among females (OR 5.80, 95% CI, 2.02-16.63) than males (OR 2.90, 95% CI, 1.44-5.82). Conclusion: Data suggest that, compared with nonpowered scooter-related injuries, powered scooter-related injuries are more often severe. This association is stronger among females than males. The higher risk of severe injury due to powered scooter use could result from increases in concussions and hip and lower extremity injuries. © 2008 Academic Pediatric Association.