4-(Acetylamino)-3-hydroxy-5-nitrobenzoic acid.

Academic Article


  • The 4-(acetylamino)-3-hydroxy-5-nitrobenzoic acid molecule, C9H8N2O6, a designed inhibitor for the influenza virus neuraminidase protein, crystallizes as hydrogen-bonded dimers. The dihedral angles of the substituent groups with respect to the planar phenyl moiety are 5.0 (3) degrees for the carboxyl group, 45.0 (2) degrees for the nitro group and 37.3 (1) degrees for the acetylamino substituent. The crystal structure is stabilized by intermolecular hydrogen bonding.
  • Digital Object Identifier (doi)

    Author List

  • Jedrzejas MJ; Luo M; Singh S; Brouillette WJ; Air GM
  • Start Page

  • 1910
  • End Page

  • 1912
  • Volume

  • 51 ( Pt 9)