Beta-chain human chorionic gonadotropin-producing leiomyosarcoma of the small intestine.

Academic Article


  • A 22-year-old patient with primary leiomyosarcoma of the small bowel presented with symptoms including nausea and vomiting, a symptom complex similar to hyperemesis gravidarum in the pregnant female. She was found to have elevated levels of serum beta-HCG which were localized to the leiomyosarcoma cells utilizing an immunoperoxidase staining technique. Thus, this patient presents evidence that beta-HCG may be produced by sarcoma cells and, therefore, that beta-HCG may be used as a tumor marker in some sarcoma patients.
  • Authors

    Published In

  • Cancer  Journal
  • Keywords

  • Adult, Antibody Specificity, Chorionic Gonadotropin, Diagnosis, Differential, Female, Histocytochemistry, Humans, Hyperemesis Gravidarum, Ileal Neoplasms, Immunoenzyme Techniques, Laparotomy, Leiomyosarcoma, Paraneoplastic Endocrine Syndromes, Pregnancy
  • Author List

  • Meredith RF; Wagman LD; Piper JA; Mills AS; Neifeld JP
  • Start Page

  • 131
  • End Page

  • 135
  • Volume

  • 58
  • Issue

  • 1