Current correction factors inadequately predict the relationship between transcutaneous (tc) and arterial PCO2 in sick neonates.

Academic Article


  • Despite widespread tcPCO2 monitoring the relationship between tcPCO2 and PaCO2 remains unclear. It has been assumed that after standard temperature correction, a constant metabolic factor can explain the elevation of tcPCO2 over PaCO2. Our data demonstrate a progressive increase in the difference between temperature corrected tcPCO2 and PaCO2 as PaCO2 increases. Thus a constant metabolic factor cannot account for the elevation of temperature corrected tcPCO2 over PaCO2. We speculate that as PaCO2 rises, CO2 production exceeds removal resulting in a progressive gradient between temperature corrected tcPCO2 and PaCO2.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Martin RJ; Beoglos A; Miller MJ; DiFiore JM; Carlo WA
  • Start Page

  • 51
  • End Page

  • 53
  • Volume

  • 220