What is the evidence for using hydroxyurea for secondary stroke prevention?

Academic Article


  • A 10-year-old male patient with hemoglobin SS suffered a stroke at 7 years of age and was initially transfused at the time of presentation to lower the hemoglobin S concentration to < 30%. You are asked by the family if their child can be treated with oral hydroxyurea rather than monthly transfusions for the secondary prevention of strokes.
  • Published In

  • Hematology  Journal
  • Digital Object Identifier (doi)

    Author List

  • Lebensburger JD; DeBaun MR; Thompson AA
  • Start Page

  • 440
  • End Page

  • 442
  • Volume

  • 2011