Cervical signet-ring cell carcinoma presenting as a synchronous primary carcinoma with uterine adenocarcinoma.

Academic Article


  • BACKGROUND: Synchronous primary gynecologic tumors are relatively uncommon with the diagnosis often made following initial surgery. CASE: A multiparous female in her 50s with postmenopausal bleeding was referred to our institution with a biopsy-proven diagnosis of endometrial cancer. Preoperative physical exam revealed a suspicious cervical lesion and upon biopsy she was found to have a signet-ring cell carcinoma of the cervix. Secondary to morbid obesity, the patient was not a candidate for a radical hysterectomy and was treated with curative radiation for stage IB 1 cervical carcinoma and clinical stage I endometrial carcinoma. CONCLUSION: Cervical signet-ring cell carcinoma is an extremely rare pathologic diagnosis. The preoperative discovery of synchronous primary gynecological tumors necessitates individualized planning and treatment.
  • Keywords

  • Adenocarcinoma, Carcinoma, Signet Ring Cell, Diagnosis, Differential, Female, Humans, Middle Aged, Neoplasms, Multiple Primary, Uterine Cervical Neoplasms
  • Digital Object Identifier (doi)

    Author List

  • Lowery WJ; Difurio MJ; Sundborg MJ; Leath CA
  • Start Page

  • 212
  • End Page

  • 213
  • Volume

  • 174
  • Issue

  • 2