Practice parameters for the diagnosis and management of immunodeficiency. The Clinical and Laboratory Immunology Committee of the American Academy of Allergy, Asthma, and Immunology (CLIC-AAAAI)

Academic Article


  • In this brief review, only the most useful immunologic tests available for defining host defects that lead to susceptibility to infection have been emphasized. It should be pointed out that those evaluations and tests ordered by the physician will rule out the vast majority of the currently recognized defects. Finally, it is important that any patients identified as abnormal by these screening tests be characterized as fully as possible in centers specializing in these diseases before therapy is initiated, since what may appear to be a simple diagnosis on the surface may be an indicator of more complex underlying problems.
  • Authors


  • Antibody Formation, Complement System Proteins, Humans, Immunity, Cellular, Immunologic Deficiency Syndromes, Phagocytes
  • Digital Object Identifier (doi)

    Author List

  • Shearer WT; Buckley RH; Engler RJ; Finn AF; Fleisher TA; Freeman TM; Herrod HG; Levinson AI; Lopez M; Rich RR
  • Start Page

  • 282
  • End Page

  • 294
  • Volume

  • 76
  • Issue

  • 3