Do Newer Monitors of Exhaled Gases, Mechanics, and Esophageal Pressure Add Value?

Academic Article


  • The current understanding of lung mechanics and ventilator-induced lung injury suggests that patients who have acute respiratory distress syndrome should be ventilated in such a way as to minimize alveolar over-distension and repeated alveolar collapse. Clinical trials have used such lung protective strategies and shown a reduction in mortality; however, there is data that these "one-size fits all" strategies do not work equally well in all patients. This article reviews other methods that may prove useful in monitoring for potential lung injury: exhaled breath condensate, pressure-volume curves, and esophageal manometry. The authors explore the concepts, benefits, difficulties, and relevant clinical trials of each. © 2008 Elsevier Inc. All rights reserved.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Owens RL; Stigler WS; Hess DR
  • Start Page

  • 297
  • End Page

  • 312
  • Volume

  • 29
  • Issue

  • 2