Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars

Academic Article

Abstract

  • Synthetic peptides and murine monoclonal antibodies were used to map cross-reactive chlamydial epitopes. A species-specific epitope in the central region of variable sequence region 4 abuts the amino-terminal end of a B- serogroup-specific or F/G-serogroup-specific epitope, which in turn abuts known serovar-specific epitopes. The carboxyl-terminal portion of variable sequence region 4 (residues 297 to 314) comprises a region of end-to-end B- cell epitopes in some serovars of the B and F/G serogroups.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Batteiger BE; Lin PM; Jones RB; Van Der Pol BJ
  • Start Page

  • 2839
  • End Page

  • 2841
  • Volume

  • 64
  • Issue

  • 7