T model of growth and its application in systems of tumor-immune dynamics

Academic Article

Abstract

  • In this paper we introduce a new growth model called T growth model. This model is capable of representing sigmoidal growth as well as biphasic growth. This dual capability is achieved without introducing additional parameters. The T model is useful in modeling cellular proliferation or regression of cancer cells, stem cells, bacterial growth and drug dose-response relationships. We recommend usage of the T growth model for the growth of tumors as part of any system of differential equations. Use of this model within a system will allow more exibility in representing the natural rate of tumor growth. For illustration, we examine some systems of tumor-immune interaction in which the T growth rate is applied. We also apply the model to a set of tumor growth data.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 12753497
  • Author List

  • Tabatabai MA; Eby WM; Singh KP; Bae S
  • Start Page

  • 925
  • End Page

  • 938
  • Volume

  • 10
  • Issue

  • 3