Cocaine-Associated Ischemic Colitis

Academic Article


  • Cocaine use can result in various gastrointestinal complications, including gastric ulcerations, retroperitoneal fibrosis, visceral infarction, intestinal ischemia, and gastrointestinal tract perforation. We report cocaine-associated colonic ischemia in three patients and review the literature. Including ours, 28 cases have been reported, with a mean patient age of 32.6 years (range, 23 to 47 years); 53.5% were men and 46.5% were women. The interval between drug ingestion and onset of symptoms varied from 1 hour to 2 days. Cocaine is a potentially life-threatening cause of ischemic colitis and should be included in the differential diagnosis of any young adult or middle-aged patient with abdominal pain and bloody diarrhea, especially in the absence of estrogen use or systemic disorders that can cause thromboembolic events, such as atrial fibrillation.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 15547572
  • Author List

  • Linder JD; Mönkemüller KE; Raijman I; Johnson L; Lazenby AJ; Wilcox CM
  • Start Page

  • 909
  • End Page

  • 913
  • Volume

  • 93
  • Issue

  • 9