The role of neural mechanisms in gastrin stimulated H+ secretion was studied using amphibian gastric fundic mucosa. Spontaneously secreting mucosae were converted to resting state (zero H+ secretory rate) using Burimamide. Following removal of burimamide, 3×10-6 M tetrodotoxin did not block gastrin stimulation of H+ secretion indicating that neural mechanisms are not required. © 1978 Birkhäuser Verlag.
