Delayed foreign-body reaction to silk sutures in pediatric neurosurgical patients

Academic Article


  • Nonabsorbable silk sutures have been a frequently used foreign material in neurosurgery. In general, they are reliable and safe with minimal bio-incompatibility. Three pediatric neurosurgical patients came to clinical attention, however, because of delayed foreign-body reactions to silk sutures. The delayed atypical presentation of these patients delayed appropriate diagnosis and therapy. In two patients, the reaction presented as a delayed inflammation 7 years following surgical suture placement. In the other patient, the reaction caused delayed recurrent shunt failures and surgical wound breakdown. These three cases are used to introduce a discussion of the delayed response of the host to foreign material and its pertinence to neurosurgery. © 1987 Springer-Verlag.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Rossitch E; Bullard DE; Oakes WJ
  • Start Page

  • 375
  • End Page

  • 378
  • Volume

  • 3
  • Issue

  • 6