Spinal cord compression as a result of Rosai-Dorfman disease of the upper cervical spine in a child

Academic Article


  • Background: Rosai-Dorfman disease is characterized by massive painless cervical lymphadenopathy, but can also include nasal obstruction, tonsillar enlargement, or hearing abnormalities. The disease occurs most often in the third and fourth decades. Most authors have suggested that it represents either an autoimmune disease or a reaction to an infectious agent that has yet to be discovered. Less than 50 cases of central nervous system involvement have been reported. Case illustration: We report a child with cervical spinal cord compression due to Rosai-Dorfman disease of the cervical spine. Prognosis: This disease has variable outcomes from relatively benign to insidious over decades. Our case is unusual in that the patient was a child and had involvement of the spine with resultant cord compression, a combination that has been reported rarely. © Springer-Verlag 2005.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 19455759
  • Author List

  • Tubbs RS; Kelly DR; Mroczek-Musulman EC; Hammers YA; Berkow RL; Oakes WJ; Grabb PA
  • Start Page

  • 951
  • End Page

  • 954
  • Volume

  • 21
  • Issue

  • 11