Cure, morbidity, and mortality associated with embolization of brain arteriovenous malformations: A review of 1246 patients in 32 series over a 35-year period

Academic Article

Abstract

  • PUBLISHED REPORTS OF cure, morbidity, and mortality associated with the embolization of 1246 brain arteriovenous malformations during the last 35 years were reviewed. Embolization resulted in cure in 5% of arteriovenous malformations. The cure rates of embolization were 4% in reports of 708 patients published before 1990 and 5% in reports of 538 patients published since 1990 (P = not significant). Temporary morbidity from embolization was 10%, and permanent morbidity was 8%. Permanent morbidity was 9% before 1990 and 8% since 1990 (P = not significant). Death after embolization of brain arteriovenous malformations occurred in 1% of patients. Mortality associated with the embolization was 2% before 1990 and 1% since 1990 (P = not significant). Long-term morbidity associated with the use of neurotoxic embolization materials is worrisome but has never been proven. Copyright © by the Congress of Neurological Surgeons.
  • Published In

  • Neurosurgery  Journal
  • Digital Object Identifier (doi)

    Author List

  • Frizzel RT; Fisher WS
  • Start Page

  • 1031
  • End Page

  • 1040
  • Volume

  • 37
  • Issue

  • 6