Determination of total body water by deuterium NMR

Academic Article

Abstract

  • A new deuterium nuclear magnetic resonance ( H NMR) method is described for determining total body water in humans. The method has been validated against a standard infrared absorption (IR) procedure using a tracer dose of deuterium oxide ( H O) of ~ 10 g for each human subject. The precision and accuracy for the methods have been compared and found to be very similar. The advantages of the H NMR method over other presently available techniques that are based on H O dilution are as follows: it is fast, accurate, needs only a small dose of H O, can be done using any body fluid, and, most importantly, does not require any sample preparation. 2 2 2 2 2 2 2 2
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Khaled MA; Lukaski HC; Watkins CL
  • Start Page

  • 1
  • End Page

  • 6
  • Volume

  • 45
  • Issue

  • 1