Role of bacteriophage MAV1 as a mycoplasmal virulence factor for the development of arthritis in mice and rats

Academic Article

Abstract

  • The lysogenic bacteriophage MAV1 has been shown to be a virulence factor for the development of arthritis in rats infected with Mycoplasma arthritidis. In the present study, arthritis was evaluated by histopathologic examination to demonstrate that MAV1 is a virulence factor not only in the rat but also in the mouse. Specifically, the MAV1 lysogen 158L3-1 was more virulent than the nonlysogen strain 158 in DBA/2NCr, C3H/HeNCr, C3H/HeJ, and C3Smn. CB17-Prkdcscid/J mice, as well as in LEW rats.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Tu AHT; Lindsey JR; Schoeb TR; Elgavish A; Yu H; Dybvig K
  • Start Page

  • 432
  • End Page

  • 435
  • Volume

  • 186
  • Issue

  • 3